Overview of Picked Chemical Compounds and Intermediates

Overview of Picked Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Utilized in the treatment method of multiple myeloma. Its synthesis or examine is vital for ensuring the purity and protection of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the treatment method of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound inside the synthesis of imatinib, a drug that targets particular different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers like breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their examine is vital for optimizing the output approach and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is applied to take care of breast cancer, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant Abiraterone is really an estrogen receptor antagonist used in the treatment method of breast most cancers. Different intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the cure of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, that have numerous programs, which include antiviral properties.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic CAS NO. 155405-80-4 Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Utilized in foodstuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication used to deal with style two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).